BackgroundBleomycin is a glycopeptide antibiotic with outstanding anti-tumor effects.A major adverse effect of bleomycin is lung fibrosis.However, the development of cataracts as a severe adverse effect has not been reported.
Case summaryHerein, we describe the first case of cataract induced by bleomycin therapy in a 22-year-old male with testicular cancer.After surgical intervention and following five successive chemotherapy Skin cycles of the BEP regimen, including bleomycin, etoposide and cisplatin, the patient reported a gradual painless loss Accessories - Socks of vision, with substantial decline in visual ability, especially in the right eye.Following comprehensive eye examinations, a cataract was diagnosed.
Eventually, the patient underwent phacoemulsification and received replacement of the intraocular lenses.ConclusionBleomycin can cause cataracts, which induces a significant loss of vision.Therefore, clinicians should observe early symptoms and properly adjust treatment to prevent aggravation of symptoms.